|
(一)国外观点
1、medhelp
(1)Edward W Hook, MD(美国专家)
Welcome back to the Forum. Your test was definitively negative and you can be sure that you did not get HIV from the exposure you experienced in May. The fact of the matter is that any test more than 8 weeks (56 days) following exposure provides definitive evidence that you were not infected. The recommendations for testing at 3 and even 6 months are the result of two factors- data from older tests no longer used (you really do not need to worry about which generation of tests you were tested with, at this time virtually all tests are far more sensitive that they were even 2-3 years ago when the 3 month recommendation was made) and secondly, the fact that some, mostly governmental agencies which have to provide recommendations for virtually everyone without the sort of interactions such as those you get with your doctor or on personalized sites such as this one, feel the cannot "afford" to be wrong and therefore make recommendations and guidelines which leave most people unnecessarily nervous for 4-6 weeks longer than the 6-8 weeks it takes virtually everyone to develop HIV antibodies.
http://www.medhelp.org/posts/HIV ... fusion/show/1341131
摘要:8周(56天)之后的检测结果完全可信,3或6月窗口期的官方提法已经过时和保守。
A DUO (Combined HIV p24 antigen/HIV antibody) test performed at 4 weeks following your exposure will give you definitive information on whether or not you got infected through this exposure.
http://www.medhelp.org/posts/HIV ... titute/show/1340521
摘要:对于第四代试剂,4周检测结果完全可信。
(2)H. Hunter Handsfield, MD(美国专家)
If you have a standard antibody test, you could be tested at 4 weeks with about 90-95% accuracy then once again at 6 weeks; or just have a single 6 week test. With the now-standard antibody tests, it is rarely necessary to test beyond 6 weeks. But follow your own provider's advice about exact tests and timing.
http://www.medhelp.org/posts/HIV ... -Groin/show/1341650
摘要:对于标准的抗体检测,4周已有99-95%准确度了,而6周则非常准确了。
All standard antibody tests in routine use are just about 100% accurate at 6 weeks, not 6 months. A negative combo test (also called a duo test) -- which measures both HIV antibody and p24 antigen, a marker of the virus itself -- is virtually 100% reliable at 4 weeks. The combo test was recently approved for use in the US, but may not yet be available in your doctor's office. But you could ask for it.
http://www.medhelp.org/posts/HIV ... mptoms/show/1338429
摘要:对于标准的抗体检测,6周已有100%准确度了;对于第四代试剂,4周检测结果完全可信。
(3)Sean Cummings, MBBS(英国专家)
I cannot explain the various different types of information you have received except to say that rapid tests are excellent and are most usually in develoed countires 3rd generation antibody tests. These are highly accurate and will correctly identify more than 99% of patients at 6 weeks post exposure. In your case you have had several of these and they have been negative - you have also had a 4th generation test and that is negative.
http://www.medhelp.org/posts/HIV ... stions/show/1339176
摘要:3代抗体检测试剂在6周有99%的准确度(他的观点3代8周)。
(4)Jose Gonzalez-Garcia(英国专家)
However if you wanted one, for peace of mind, I would recommend a HIV Duo or Combo at 4 weeks, or and antibody test after 8 weeks.
http://www.medhelp.org/posts/HIV ... stress/show/1320834
摘要:4代4周,3代8周完全排除。
(5)Lizzie Lou和Teak(资深志愿者)
他们坚持3个月完全排除,尤其是Teak,而Lizzie Lou认为6周有积极意义。
2、USA CDC(美国疾控中心)
Most people will develop detectable antibodies that can be detected by the most commonly used tests in the United States within 2 to 8 weeks (the average is 25 days) of their infection.
http://www.cdc.gov/hiv/topics/basic/
摘要:2-8周内(平均25天)绝大多数为可检出抗体。
3、联合国卫生署
This is the time between original infection with HIV and the appearance of Detectable antibodies to the virus, normally a period of about 14-21 days.
http://www.who.int/diagnostics_laboratory/faq/window_period/en/
摘要:窗口期平均14~21天
4、美国红十字会
basic answer: before getting tested, it is useful for people to wait three months from the time they think they may have been infected with hiv (the virus that causes aids). this is enough time for most people to develop antibodies to hiv (the average time is 25 days.) otherwise, people may test negative even though they have hiv. this is called the "window period."
摘要:一般从高危三个月后进行测试是有效的。对于大多数人来说(平均25天)是可以产生足够的抗体.但也有可能是假阴,这就称为“空窗期”。
http://www.redcross.org/services/hss/tips/waittest.html
5、纽约护士协会
most people infected with hiv will develop enough antibodies to be detected by our current hiv antibody tests four weeks after the exposure.
摘要:用现行的抗体测试方法,大多数人在感染后4周就可产生足够的抗体了.
http://www.nysna.org/programs
6、PNAS:美国科学院院报(权威学术论文)
论文主要研究艾滋病毒(HIV-1)早期感染与传播的鉴别问题,2008年发表在PNAS期刊上的论文,被引用次数为151次。
其窗口期实验结果是:
(1)大约在感染10天左右可以检测到病毒的核酸RNA。
(2)18天左右起可以检测到P24抗原,大约在35天后消失,4代试剂的优势也就是在这个阶段可以早发现感染者。
(3)22天左右,可以用3代酶联检测到抗体。
(4)25天左右可以用免疫印迹确证实验查HIV抗体。
http://www.ncbi.nlm.nih.gov/pmc/ ... 184/pdf/zpq7552.pdf
|
|